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Chapter 14
Building Biotechnology
Doriot's Rules of Investing
Seek companies demonstrating:
  • New technology, new marketing concepts, and new application possibilities
  • A significant participation by investors in management
  • Staff of outstanding competence and integrity
  • Products or processes that have been prototyped and have intellectual property protection
  • Promise to enable an initial public offering or sale of company within a few years
  • Opportunity for a venture capitalist to add value beyond dollars invested
General Georges Doriot of American Research & Development, the first dedicated venture capital firm

Successful biotechnology business development relies on three factors: technology, management, and capital. The essential value proposition of biotechnology companies is to develop applications based on proprietary technologies, granting them monopolies on the products of their R&D investments. Management is responsible to identify commercial possibilities for the markets a company wishes to target and position the company to realize them. Capital is required to fund research and development and ultimately enable commercialization.
An examination of the qualities sought by offices experienced in launching biotechnology companies provides practical examples of factors important for long-term success. According to the MIT’s Technology Licensing Office, 'Positive indicators include very early-stage research, a technology that has several potential applications, no existing companies dominating the field, and an inventor who wants to participate actively in his or her invention's commercialization.' They observe that emerging technologies with multiple new markets are often best exploited by focused and dedicated entrepreneurs who are funded by venture capitalists with an understanding of technical and business risk and reward.
Manchester Innovation Ltd., a technology transfer arm and incubator

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